Best Ointments for Anal Fissures

In today’s post, we will be talking about the best ointments for anal fissures and how they can help to treat them effectively.

Note: you can use q-tips or doserite applicators instead of your finger to apply the ointment internally or externally around the area affected (consult your doctor).

Nitroglycerin ointment is a nitrate vasodilator used to treat moderate to severe pain associated with chronic anal fissures. It is commonly prescribed by doctors and recommended by many people.

It comes in 0.4% and you can apply 1 inch of the ointment (375 mg of ointment equivalent to 1.5 mg of
nitroglycerin) intra-anally every 12 hours for up to 3 weeks.

2. Nifedipine ointment

Nifedipine ointment is another prescription medicine used for the treatment of anal fissures. Nifedipine works by relaxing the smooth muscle of the internal anal sphincter to promote fissure healing.

Your doctor will prescribe Nifedipine as a 0.2% ointment. The ointment should be used twice daily, once in the morning and once at night. Nifedipine has few associated side effects.

You can also get Nifedipine ointment along with another ingredient called Lidocaine.

3. Diltiazem ointment

Diltiazem ointment is a calcium channel blocker that is used to help heal anal fissures, promote wound healing, or treat external thrombosed hemorrhoids. The ointment relaxes the smooth muscle around the rectum and promotes blood flow to help the growth of new skin over the tear in the lining of the rectum. The ointment reduces anal canal pressure, which diminishes pain and spasm. We use a 2% concentration mixed with Lidocaine and Aloe Vera. It is only available at compounding pharmacies.

For anal fissures, the ointment should be applied three times a day usually for six weeks, and then one to two times a day for usually an additional six weeks. A

4. Calmoseptine Ointment

This is an ointment you can get over the counter and provides temporary relief of local itching and discomfort in the perianal area, pain or burning, and skin irritations.

Apply the ointment externally to the affected area up to 6 times daily or after each bowel movement

Active Ingredients include: lanolin 15.7%, menthol 0.44%, petrolatum 24%, and zinc oxide 20.6%

Inactive Ingredients include: calamine, chlorothymol, glycerin, phenol, sodium bicarbonate, and thymol in a suitable ointment base.

5. Glyceryl trinitrate (GTN) rectal ointment

This is another ointment that helps to reduce the fissure and relieve the pain and spasm associated with this condition.

When applying the ointment, a 1 cm to 1.5 cm strip of ointment should be inserted into the anal cavity with your finger. You can apply the ointment three times daily and do not exceed the dosage.

6. Terrasil Anti-Bacterial Skin Repair Ointment

Terrasil Anti-Bacterial Skin Repair is a soothing ointment that kills bacteria and promotes the rapid healing of fissures, boils, sores, blisters, cellulitis, cysts, and folliculitis.

  • It kills bacteria up to 3x faster
  • It promotes healing and can help with lichen sclerosis and angular cheilitis
  • It soothes itching, calms inflammation, and redness
  • You can see improvement within 1 to 2 days

7. Other ointments and creams

  • H-fissures formula
  • Emuaidmax First Aid Ointment 
  • Calendula cream
  • Zinc oxide-based creams

Which of these ointments would be suitable for me?

Nitroglycerin ointment, nifedipine ointment, diltiazem ointment, and glyceryl trinitrate (GTN) rectal ointment are some medicines that doctors would prescribe to their patients.