What is JADELLE? How does JADELLE work? JADELLE prevents pregnancy in different ways. JADELLE stops the release of an egg from your ovary. JADELLE also thickens the mucus in your cervix, and this stops the sperm from reaching the egg. It also thins the lining of the uterus. Do not use JADELLE if you: How are the JADELLE implants placed? Before having JADELLE placed, tell your doctor if you: Initiating Contraception with JADELLE: When should I call my doctor, after the JADELLE has been placed? What are the most common side effects of JADELLE? What are some serious side effects of JADELLE? The following side effects have been identified during…

What is YONDELIS? YONDELIS is a prescription medicine used to treat people with liposarcoma or leiomyosarcoma that:• has spread to other areas of the body, or cannot be treated with surgery, and• who has received treatment with other certain medicines. It is not known if YONDELIS is safe and effective in children. What are the ingredients in YONDELIS? Active ingredient: trabectedinInactive ingredients: potassium dihydrogen phosphate, sucrose, potassium hydroxide, and phosphoric acid. How should I store YONDELIS? Store YONDELIS vials in a refrigerator at 2°C to 8°C (36°F to 46°F). YONDELIS is a cytotoxic drug (handle with care). Who should not receive YONDELIS? You will not receive YONDELIS if you have…

What is YONSA? YONSA is a CYP17 inhibitor indicated in combination with methylprednisolone for the treatment of patients with metastatic castration-resistant prostate cancer. Before taking YONSA, tell your doctor about all of your medical conditions, including if you: have heart problems have liver problems have diabetes have a history of adrenal problems or have a history of pituitary problems are receiving any other treatment for prostate cancer are pregnant or planning to become pregnant. YONSA can cause harm to your unborn baby and miscarriage. Females who are pregnant should not handle YONSA tablets if broken, damaged, crushed, or without protection, such as gloves. have a partner who is pregnant or…

What is YOSPRALA? YOSPRALA is a combination of aspirin (anti-platelet agent), and omeprazole (proton pump inhibitor (PPI), for patients who require aspirin for preventing cardiovascular and cerebrovascular events for the second time and who are at risk of developing aspirin-associated gastric ulcers. The aspirin component of YOSPRALA was indicated for: reducing the combined risk of death and nonfatal stroke in patients who have had transient ischemia or ischemic stroke of the brain due to fibrin platelet emboli, reducing the combined risk of death and nonfatal MI in patients with a previous MI or unstable angina pectoris, reducing the combined risk of MI and death in patients with chronic stable angina…

Yasmin is a prescription medicine used to treat Premenstrual Dysphoric Disorder (symptoms such as anxiety, irritability, trouble concentrating, lack of energy depression, sleep, joint or muscle pain, headache appetite changes, breast tenderness, and weight gain.), moderate acne (in girls who are at least 14 years of age and have started getting their periods and plans to use birth control pills), and prevent pregnancy. It is a combination of two hormones: estrogen (Ethinyl estradiol) and progestin (Drospirenone) and is prescribed as a combined oral contraceptive consisting of 21 light yellow tablets with active ingredients and 7 white inactive tablets. How to use YASMIN? The YASMIN pack contains 21 active tablets and 7 inactive tablets (28…

YUTIQ or fluocinolone acetonide intravitreal implant 0.18 mg is indicated for the treatment of chronic non-infectious uveitis that affects the posterior segment of the eye. What should I know before I use YUTIQ? CONTRAINDICATIONS Hypersensitivity: YUTIQ is contraindicated in patients with known hypersensitivity to this product. Ocular or Periocular Infections: YUTIQ is contraindicated in patients with active or suspected ocular or periocular infections including most viral disease of the cornea and conjunctiva including vaccinia, mycobacterial infections, varicella, active epithelial herpes simplex keratitis (dendritic keratitis), and fungal diseases. WARNINGS AND PRECAUTIONS Intravitreal Injection-related Effects: Intravitreal injections, including YUTIQ, have been associated with increased or decreased intraocular pressure, endophthalmitis, eye inflammation, and choroidal or retinal detachments. Hypotony has…

What is YUSIMRY? YUSIMRY is a medicine called a Tumor Necrosis Factor (TNF) blocker. YUSIMRY is used To reduce the signs and symptoms of: Moderate to severe Rheumatoid Arthritis in adults: YUSIMRY can be used alone, with methotrexate, or with certain other medicines. Moderate to severe Polyarticular juvenile idiopathic arthritis: in children 2 years and older. YUSIMRY can be used alone or with methotrexate. Psoriatic arthritis in adults: YUSIMRY can be used alone or with certain other medicines. Ankylosing spondylitis in adults. To treat moderate to severe Crohn’s disease: in adults and children 6 years of age and older. To treat moderate to severe Ulcerative colitis in adults: It is…

What is YUPELRI? YUPELRI is a prescription medicine used to treat chronic obstructive pulmonary disease (COPD), a long-term chronic lung disease that includes emphysema, chronic bronchitis, or both. It is an anticholinergic (blocking the action of a neurotransmitter called acetylcholine) medicine that helps the muscles around the airway in your lungs stay relaxed to prevent symptoms such as cough, chest tightness wheezing, and shortness of breath. It is used long-term and it is in the form of a vial (1 time each day). It is inhaled through your nebulizer to improve symptoms of COPD for better breathing. What are the ingredients in YUPELRI? Active ingredient: revefenacin Inactive ingredients: sodium chloride,…

Secukinumab can help in the treatment of moderate to severe Papulopustular rosacea by binding IL-17A and neutralizing its pro-inflammatory effect. This can be explained by looking at a study: In an open-label, single-arm trial, 23 participants were dosed with 300 mg secukinumab during a 5-week period. A maintenance period of 2-months was followed with final endpoints at 16 weeks. Study results showed participants with 20 papules had a larger papule count reduction when compared to participants who presented with fewer papules at week 0. Further, participants with severe rosacea saw a 43% papule reduction vs. a 10% papule reduction in participants presenting with lower severity. Conclusion: Secukinumab for rosacea showed significant improvements…

Let’s look at a study and see how sarilumab can be effective in treating modulate mild to severe COVID-19-associated CRS. This study consists of 5 SARS-CoV-2 elderly patients (3 men and 2 women) with good quality of life. Previous to the outbreak, when first admitted to the hospital, they received hydroxychloroquine and azithromycin. They were considered candidates for sarilumab when they presented increased oxygen needs radiological progression, and worsening of biological parameters. Four of them were on noninvasive ventilation and 1 was on invasive mechanical ventilation. The decrease in lymphocyte count significantly improved after a single dose of sarilumab 200 mg. Two patients died 1 with (previous chronic obstructive pulmonary disease…