DUAC Gel for Acne Vulgaris

DUAC Gel is a combination of clindamycin phosphate and benzoyl peroxide indicated for the topical treatment of inflammatory acne vulgaris.

Limitation of Use:

DUAC Gel does not have any additional benefit when compared with benzoyl peroxide alone in the same vehicle when used for the treatment of non-inflammatory acne.

Do not use DUAC Gel if you have:

• had an allergic reaction to clindamycin, lincomycin, benzoyl peroxide, or any of the ingredients in DUAC Gel.

• Crohn’s disease or ulcerative colitis.

• had inflammation of the colon with past antibiotic use.

Before using DUAC Gel, tell your doctor about all of your medical conditions, including if you:

• plan to have surgery with general anesthesia.

• are sensitive to sunlight.

• are pregnant or planning to become pregnant. It is not known if DUAC Gel can harm your unborn baby.

• are breastfeeding or planning to breastfeed. It is not known if DUAC Gel can pass into your breast milk. One of the active ingredients in DUAC Gel is clindamycin. Clindamycin when taken by injection or mouth by injection has been reported to appear in breast milk.

• You and your doctor should decide if you will use DUAC Gel while breastfeeding.

• Tell your doctor about all the medicines you take, including prescription or over-the-counter medicines, vitamins, herbal supplements, and skin products you use. Using other topical acne products may increase the irritation of your skin when used with DUAC Gel.

• Tell your doctor if you take a medicine that contains erythromycin. DUAC Gel should not be used with products that contain erythromycin.

• Use DUAC Gel exactly as your doctor tells you to use it.
• Before applying DUAC Gel, wash your face gently with a mild soap, rinse with warm water, and pat the skin dry.
• Apply a thin layer of DUAC Gel to your face 1 time a day, in the evening, or as directed by your doctor. Wash your hands with soap and water after applying DUAC Gel.

Do not get DUAC Gel in your eyes, nose, mouth, vagina, or on your lips. Do not get DUAC Gel on open wounds or cuts.

What should I avoid while using DUAC Gel?

• Make sure to limit your time in sunlight. Avoid using tanning beds or sun lamps. Wear a wide-brimmed hat or other protective clothing when going out in the sun.

• Sunscreen may also be used.

• Talk to your doctor if you spend a lot of time in the sun.

• DUAC Gel may bleach colored fabric or hair.

The most common side effects of DUAC Gel are skin reactions and may include peeling, dryness, redness, and burning. These are not all the possible side effects of DUAC Gel.

DUAC Gel may cause serious side effects, including:

• Inflammation of the colon (colitis): Stop using DUAC Gel and call your doctor right away if you have severe watery diarrhea or bloody diarrhea.

• Allergic reactions: Stop using DUAC Gel and call your doctor or get help right away if you have any of the following symptoms:
  • severe itching
  • swelling of your eyes, lips, face, tongue, or throat
  • trouble breathing

• Store DUAC Gel at room temperature up to 25°C. Do not freeze DUAC Gel.

• The expiration date of DUAC Gel is 60 days from the date when you fill your prescription.

• Throw away expired DUAC Gel.

• Keep the tube tightly closed.

Active Ingredients: clindamycin phosphate 1.2% and benzoyl peroxide 5%
Inactive ingredients: carbomer homopolymer (type C), dimethicone, glycerin, methylparaben, disodium lauryl sulfosuccinate, edetate disodium, silicon dioxide, poloxamer 182, purified water, and sodium hydroxide.

Yes, duac gel can cause purging because it promotes cell turnover rate. It can cause peeling, dryness, redness, and burning