Lupoid perioral dermatitis

Lupoid perioral dermatitis is a special form of perioral dermatitis with dense aggregations of red-brown papules which display a lupoid infiltrate on diascopy (a piece of clear glass or plastic is pressed against the skin and the observer looks directly at the lesion under pressure).

There are various treatment options from avoidance of all topical substances to different topical treatments. Cases resistant to therapy require systemic treatment, which, however, is an off-label use.

In one case, lupoid perioral dermatitis was treated with systemic therapy with isotretinoin over a period of 6 months.