Rozex gel (metronidazole 0.75%) for Rosacea

Rozex gel or metronidazole gel is used for the treatment of inflammatory lesions (papules and pustules) of rosacea.

it should only be used in adults who are 18 years and above.

What does it contain?

Each gram of Rozex gel contains 7.5 mg/g of metronidazole as the active ingredient.

Inactive ingredients: methyl hydroxybenzoate, Carbomer 940, propyl hydroxybenzoate, disodium edetate propylene glycol, sodium hydroxide to adjust pH, and purified water q.s. to 1.0g.

Metronidazole has antibacterial and anti-inflammatory properties and belongs to the class of medicines known as antibacterial and antiprotozoals.

Rozex gel can also be used in combination with oral medications prescribed by your doctor.

Your doctor may also prescribe Rozex gel for another reason, so if you have any questions, you can ask your doctor.

What should I tell my doctor before I use Rozex gel?

  • if you have an allergy to the active (metronidazole) or any of the inactive ingredients in the gel Symptoms of an allergic reaction may include:
    • swelling of the lips, tongue, face, or other parts of the body
    • hives of the skin, rash, and itching, especially on the areas of the skin where the cream was applied.
  • if you have or had a blood disorder
  • if you’re using the gel to treat your child’s skin problem. Rozex gel has not been used in children and treated
  • if you are pregnant or planning to become pregnant. There are no well-controlled studies of therapy with Rozex gel in pregnant women.
  • if you are breastfeeding. Rozex gel may pass into your breast milk.
  • Tell your doctor about all the medicines you take, including skin products, vitamins, prescriptions, over-the-counter medicines, and herbal supplements. Using Rozex gel with certain other medicines can cause serious side effects.

What are the side effects of using Rozex gel?

Mild side effects:

  • dry skin
  • superficial reddening of the skin
  • severe itching of the skin
  • skin discomfort (burning, dryness, pain of skin/stinging)
  • skin irritation
  • worsening of rosacea
  • hyperpigmentation and other pigmentation disorders
  • contact dermatitis
  • reduced sense of touch or sensation
  • tingling sensation
  • numbness in the extremities
  • dysgeusia (metallic taste)
  • seborrhea (red, itchy rash and white scales)
  • sunburn, skin infection, hives
  • gastritis, bronchitis
  • stuffy, runny nose
  • skin exfoliation, swelling face
  • nausea, excess water fluid collection on the face or eyelids

Uncommon or rare side effects:

  • hypothyroidism
  • Bursitis (inflammation or irritation of the bursa)
  • Myalgia (muscle pain)
  • osteoporosis
  • conjunctivitis
  • abscess

How to use Rozex gel?

You can apply the Rozex gel in the morning and evening to a dry, clean face. Apply a pea-sized amount to the affected areas of your face. Do not use Rozex gel in your eyes, mouth, lips, or vagina. Remember to use sunscreen.

You can continue to use the gel even though there may not be an immediate effect. Medicines can take several weeks to show. The average period of treatment is usually three to four months and the recommended duration of treatment should not be exceeded.

You can apply makeup over Rozex gel and If you forget to apply Rozex gel use it again as directed, as soon as you remember.

Things you shouldn’t do when using Rozex gel:

  • Do not use cosmetic products that contain alcohol as they may dry or irritate the skin.
  • Do not use medicated soaps. These may have a drying or irritant effect on the skin.
  • It is not known if Rozex gel can increase the chance of skin cancers developing in people who have excessive exposure to sunlight. Therefore you should avoid or minimize exposure of areas of your skin treated with Rozex gel to sunlight or other sources of UV light.
  • Rozex gel should not be used long-term.


Use Rozex gel less frequently if your face becomes itchy, hot, red, or swollen. Do not exceed the recommended duration of treatment.

Do not use Rozex gel after the expiry date printed on the pack or if the packaging is torn or if there are signs of tampering. If it has expired or is damaged, return it to your doctor for disposal.


  • Keep the medicine in places where the temperature stays below 25°C.
  • Keep the medicine away from children.
  • Do not leave it in the car as heat can destroy the medicine.

Frequently Asked Questions:

Can Rozex gel be used for perioral dermatitis?

Yes, rozex gel can be used for the treatment of perioral dermatitis mainly because of its anti-inflammatory and antibacterial properties. You can use it 2 times a day (morning and night). Note that there will be a purging effect.

Can Rozex gel be used for seborrheic dermatitis?

Yes, rozex gel or metronidazole gel is an effective treatment for facial seborrheic dermatitis.

Can Rozex gel be used for wound healing and wound odor?

Yes, rozex or metronidazole gel is effective in wound healing and wound odor along with healing infections.