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Arylia (Denosumab) for Treatment of Osteoporosis and Bone Loss
What is Arylia and what is it used for? Arylia contains the active ingredient Denosumab. Denosumab is a human monoclonal antibody that targets and binds with high affinity and specificity to RANKL. RANKL is a protein that is necessary for the function, formation, and survival of osteoclast. Arylia stops RANKL from activating its receptor RANK, present on the surface of osteoclasts. This prevents osteoclast function, formation, and survival, hence decreasing resorption of bone and increasing bone mass and strength. It is used to treat: Osteoporosis in postmenopausal women and in men at increased risk of fractures. Bone loss associated with hormone ablation in men with prostate cancer at increased risk…
Altebrel (Etanercept) – For Treatment of Various Inflammatory Diseases
What is Aletebrel and what does it treat? Altebrel contains the active ingredient called Etanercept with protein structure. It belongs to a group of medicines called Tumor Necrosis Factor (TNF) Blocking Agent. Altebrel is produced by recombinant DNA technology in a Chinese Hamster Ovary (CHO). This medicine blocks the activity of TNF-α and as a result, helps to improve the inflammation process in your body. It is used to treat: Rheumatoid Arthritis: Altebrel helps in the treatment of moderate to severe Rheumatoid Arthritis in adults. If you did not respond well to other treatments, you will be given Altebrel in combination with Methotrexate. If Methotrexate is not appropriate for the…
AryoSeven (rFVIIa) for Treatment of Bleeding Episodes
What is AryoSeven and what is it used for? AryoSeven contains the active substance called Eptacog alfa belonging to a group of medicines called blood coagulation factors involved in blood clotting. It is vitamin k-dependent and works by activating the extrinsic pathway of coagulation. It is similar to the human plasma-derived factor Vlla. AryoSeven is used for the treatment and prevention of bleeding episodes during surgical operations for the following indications: Congenital Haemophilia A or B with inhibitors Acquired Haemophilia Congenital FVII deficiency Who should not use AryoSeven? If you ever had an allergic reaction to Eptacog alfa or any of the ingredients in AryoSeven. If you ever had an…
ReciGen (Interferon beta-1a) for Multiple Sclerosis
What is ReciGen? ReciGen (interferon beta-1a) is made from human proteins and helps the body fight viral infections. What is ReciGen used for? ReciGen is used to treat relapsing multiple sclerosis (MS) and will help to decrease the frequency of relapse symptoms. Who should not use ReciGen? You should not use ReciGen if you are allergic to interferons or human albumin. What should I tell my doctor before taking ReciGen? Tell your doctor if you have: liver disease; epilepsy or other seizure disorder; heart disease, chest pain (angina); a history of blood clots or bleeding disorder; a thyroid disorder; or a history of depression or suicidal behavior. are pregnant or planning to become pregnant.…
CinnoVex (interferon beta-1a) for Multiple Sclerosis
What is CinnoVex? CinnoVex (interferon beta-1a) is made from human proteins and helps the body to fight viral infections What is CinnoVex used for? CinnoVex is used to treat relapsing multiple sclerosis (MS) and decrease the frequency of relapse symptoms Who should not use CinnoVex? You should not use CinnoVex if you are allergic to interferons, human albumin, or any of the ingredients present in CinnoVex. Pre-filled syringe products of CinnoVex are albumin-free. What should I tell my doctor before taking CinnoVex? Before using CinnoVex, tell your doctor if you liver disease; epilepsy or other seizure disorder; heart disease, chest pain (angina); history of blood clots or bleeding disorder; a thyroid disorder; or a…
CinnoTec (Dimethyl Fumarate) for Multiple Sclerosis
What is CinnoTec? CinnoTec (dimethyl fumarate) is a prescription medicine used to treat relapsing multiple sclerosis. What is CinnoTec used for? CinnoTec (Dimethyl fumarate) is used to treat patients with relapsing forms of multiple sclerosis. Who should not use CinnoTec? You should not use CinnoTec if you are allergic to dimethyl fumarate or any of the ingredients in CinnoTec. What should I tell my doctor before using CinnoTec? are pregnant or planning to become pregnant. It is not known if CinnoTec can harm your unborn baby. are breastfeeding or planning to breastfeed. It is not known whether CinnoTec can pass into your breast milk. How to use CinnoTec? You can take CinnoTec with or…
CinnoRA (Adalimumab)
What is CinnoRA used for? CinnoRA is used to reduce signs and symptoms of rheumatoid arthritis (RA). Your doctor will decide if CinnoRA can be used alone or in combination with other medications. CinnoRA can also be used in juvenile idiopathic arthritis (≥2 years of age), ulcerative colitis, plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, non-infectious uveitis in adults and children (≥2 years of age), Crohn’s disease in adults or children (≥6 years of age), and hidradenitis suppurativa in adults and adolescents (≥12 years of age). Who should not use CinnoRA? Do not use CinnoRA if: You are allergic to adalimumab or any components of the CinnoRA formulation. You have severe active infections. You have moderate to severe…
Xacrel (Ocrelizumab) for Multiple Sclerosis
What is Xacrel (Ocrelizumab)? Xacrel (Ocrelizumab) is a humanized monoclonal antibody that targets and removes CD20 positive B lymphocytes which contribute to nerve damage in MS. When these targeted B cells are removed, inflammation is reduced and the chance of other nerve cells being affected is lessened. What is Xacrel used to treat? It is used to treat adults with: Relapsing forms of multiple sclerosis (RMS) Primary progressive multiple sclerosis (PPMS) Who should not take Xacrel? You must not be given Xacrel if you: Are allergic to ocrelizumab or any of the other ingredients of this medicine. Currently have an infection Have been told that you have severe problems with your…
BESPONA injection (inotuzumab ozogamicin) for Acute Lymphoblastic Leukemia
What is BESPONSA? BESPONSA is a prescription medicine used to treat adults with relapsed or refractory B-cell acute lymphoblastic leukemia (ALL). It is not known if BESPONSA is safe to use in children under 18 years of age. Contraindications None. What should I tell my doctor before taking BESPONSA? Before taking BESPONSA, tell your doctor about all of your medical conditions, including if you: Have liver disease or a history of liver problems Have an infection Have ever experienced symptoms such as chills, rash, fever, or breathing problems during or shortly after your BESPONSA infusion have signs and symptoms of tumor lysis syndrome, which may be associated with symptoms in the stomach…
Lunsumio (mosunetuzumab) for Follicular Lymphoma
What is Lunsumio and what it is used for? Lunsumio is used to treat adults who have a blood cancer called follicular lymphoma (FL). Lunsumio is given to patients who have tried at least two previous treatments for FL when either cancer has not responded to them, or it has come back again. Lunsumio contains the active substance, mosunetuzumab, which is a monoclonal antibody, a type of protein that attaches to specific targets in the body. In this case, mosunetuzumab attaches to a target substance found on B cells, including the cancerous B cells, and another target found on ‘T cells, a different type of white blood cell. T cells…