YUSIMRY (Adalimumab-aqvh) for Inflammatory Diseases
What is YUSIMRY? YUSIMRY is a medicine called a Tumor Necrosis Factor (TNF) blocker. YUSIMRY is used To reduce the signs and symptoms of: Moderate to severe Rheumatoid Arthritis in adults: YUSIMRY can be used alone, with methotrexate, or with certain other medicines. Moderate to severe Polyarticular juvenile idiopathic arthritis: in children 2 years and older. YUSIMRY can be used alone or with methotrexate. Psoriatic arthritis in adults: YUSIMRY can be used alone or with certain other medicines. Ankylosing spondylitis in adults. To treat moderate to severe Crohn’s disease: in adults and children 6 years of age and older. To treat moderate to severe Ulcerative colitis in adults: It is…
YUPELRI (Revefenacin) – for the treatment of Chronic Obstructive Pulmonary Disease (COPD)
What is YUPELRI? YUPELRI is a prescription medicine used to treat chronic obstructive pulmonary disease (COPD), a long-term chronic lung disease that includes emphysema, chronic bronchitis, or both. It is an anticholinergic (blocking the action of a neurotransmitter called acetylcholine) medicine that helps the muscles around the airway in your lungs stay relaxed to prevent symptoms such as cough, chest tightness wheezing, and shortness of breath. It is used long-term and it is in the form of a vial (1 time each day). It is inhaled through your nebulizer to improve symptoms of COPD for better breathing. What are the ingredients in YUPELRI? Active ingredient: revefenacin Inactive ingredients: sodium chloride,…
What is Gnathophyma rosacea?
Gnathophyma rosacea is a rare subtype of rosacea that results in the swelling of the chin. What is the treatment for Gnathophyma rosacea? Possible topical treatments include metronidazole cream, azelaic acid, atenolol, and clonidine Possible oral antibiotics include metronidazole, clarithromycin, minocycline, doxycycline, cephalosporins, ivermectin, and oral isotretinoin. But, only antibiotics and oral isotretinoin can reduce phymas. To treat severe types of phymas one can make use of carbon dioxide laser and surgery. Note: make sure to consult a professional dermatologist as they can only the best treatment that is suitable for you.
What is Otophyma rosacea?
Otophyma rosacea is a rare subtype of rosacea that results in disfigurement of the outer ears. This subtype of rosacea is seen more in men than women. In very rare cases otophyma may cause conductive hearing loss because of the obstruction of the external auditory canal. Otophyma rosacea can be seen as edematous swelling with or without erythema and peau d’orange appearance is characteristic while papules and pustules are absent. What is the treatment for Otophyma rosacea? Debulking surgery is an option with excision of the lymphedematous skin, and Defect closure by free skin transplant. Defect closure can be done with split-skin or full-skin transplants. Decortication is another surgical option…
What is Metophyma rosacea?
Metophyma rosacea is a subtype of rosacea that affects the forehead and results in swelling. What is the treatment for Metophyma rosacea? Early identification and treatment can help with metophyma rosacea. Topical treatments (like metronidazole cream, azelaic acid, atenolol, and clonidine) and oral antibiotics (like metronidazole, clarithromycin, minocycline, doxycycline, cephalosporins, ivermectin, and oral isotretinoin) may help. But, treatments will vary depending on the severity of your phyma. Metophyma is a rare subtype and only an experienced and professional dermatologist can really provide proper treatment for you.
What is Papulopustular rosacea?
Papulopustular rosacea is a subtype of rosacea that is mistaken for acne. It begins with pus-filled blemishes or swollen bumps that form together on your skin. They appear mainly on the cheeks, forehead, and chin. What causes Papulopustular rosacea? Sunlight Smoking Spicy food, hot drinks, and chocolate High temperatures. Alcohol High stress Exercise Some medications and supplements. What are the symptoms of Papulopustular rosacea? flushing Swelling, and breakouts that resemble acne. What is the treatment for Papulopustular rosacea? Combining topical treatments with oral antibiotics is the treatment for papulopustular rosacea. Topical treatments: Topical treatments include metronidazole, ivermectin, azelaic acid, and dapsone. Metronidazole: Metronidazole works as an anti-inflammatory drug by changing neutrophil…
Phymatous rosacea – A rare subtype of rosacea
Phymatous rosacea also known as Rhinophyma rosacea is a rare disfiguring disease that affects the nose. Other phymas include otophyma (it affects the ears), metophyma (it affects the forehead), gnathophyma (it affects the chin), and blepharophyma (eyelids). There are 4 types of rhinophyma that include fibrous, glandular, fibroangiomatous, and actinic. Phymatous rosacea was thought to be caused by heavy alcohol use, but phymatous occurs equally in people who do not use alcohol and those who drink heavily. The only problem is that it is much more common in men than in women. What causes Phymatous rosacea? What are the symptoms of Phymatous rosacea? What triggers Phymatous rosacea? What is the…
What is Erythematotelangiectatic Rosacea?
Erythematotelangiectatic rosacea is a subtype of rosacea most characterized by its flushing, background erythema, and telangiectasia. It may also be accompanied by burning, stinging, or facial edema. What causes Erythematotelangiectatic Rosacea? Erythematotelangiectatic Rosacea arises from a dysregulation in the cutaneous vasomotor response, triggered by hormonal, thermal neurogenic, topical, or other stimuli and it results in an abnormal and persistent dilation of facial blood vessels. What is the current treatment for Erythematotelangiectatic Rosacea? Topical treatments like metronidazole, oxymetazoline hydrochloride, 0.05%, laser therapy, azelaic acid, and brimonidine can also be used to treat erythematotelangiectatic rosacea. Metronidazole: Metronidazole works as an anti-inflammatory drug by changing neutrophil chemotaxis and inactivating reactive oxygen species. Metronidazole…
Can Secukinumab treat Papulopustular rosacea?
Secukinumab can help in the treatment of moderate to severe Papulopustular rosacea by binding IL-17A and neutralizing its pro-inflammatory effect. This can be explained by looking at a study: In an open-label, single-arm trial, 23 participants were dosed with 300 mg secukinumab during a 5-week period. A maintenance period of 2-months was followed with final endpoints at 16 weeks. Study results showed participants with 20 papules had a larger papule count reduction when compared to participants who presented with fewer papules at week 0. Further, participants with severe rosacea saw a 43% papule reduction vs. a 10% papule reduction in participants presenting with lower severity. Conclusion: Secukinumab for rosacea showed significant improvements…
What does my hair need? Is it Moisture, Hydration, or Conditioning
In general, we interpret moisturizing/hydrating as the act of adding water to our hair. But, this is a bad idea as adding water to our hair can lead to damage and make the hair vulnerable. Wet hair without conditioning agents is more vulnerable and research has actually shown that hair containing higher percentages of water feels more dry/brittle/rough and hair with lower percentages is seen as more smooth. So, what should we do with our hair? We should condition it of course. We need to add ingredients to our hair that stick to the hair and coat it. In this way, we can make the hair smooth, easy to detangle,…